Sunday, August 27, 2006

Glucose Intolerance: Condition, Symptoms

Glucose Intolerance: Condition, Symptoms

Glucose intolerance in a condition where symptoms may not appear for prolonged periods of time (e.g., years) and some of the early symptoms may be ignored or passed off by the patient as nagging, but inconsequential, physical conditions. Glucose intolerance is part of syndrome X, which is a medically recognized collection of conditions including insulin resistance, increased levels of circulating insulin in the blood, obesity, high blood pressure, and high blood cholesterol levels. The obesity is frequently manifested in an "apple" shaped body, with the excess weight (fat) concentrated around the middle of the body.

"The major categories of the disorders of glycemia or glucose tolerance are type 1 diabetes mellitus, type 2 diabetes mellitus, other specific types of diabetes, gestational diabetes mellitus (GDM), impaired glucose tolerance (IGT), and impaired fasting glucose (IFG). Conditions secondarily associated with glucose intolerance also occur.

* * * * *

* Impaired glucose tolerance (IGT) and impaired fasting glucose:

-- Patients with impaired glucose homeostasis are generally asymptomatic.

-- Features of related risk factors for cardiovascular disease may be present, even with a mild degree of hyperglycemia. They include a history of hypertension; a history of obesity; a history of dyslipidemia; and a history of macrovascular disease such as stroke, coronary disease, or peripheral vascular disease.

-- In most cases of IGT and impaired fasting glucose, the presence of one or more cardiovascular risk factors actually triggers a screening test for disorders of glucose tolerance.

* Glucose intolerance: Diagnosis of glucose intolerance may also be coincidental in patients with various conditions that may be complicated with glucose intolerance. These conditions include liver cirrhosis, end-stage renal disease, and some of the rare genetic disorders.

* Gestational diabetes mellitus: This is typically detected during routine screening of pregnant women for glucose intolerance. Any degree of glucose intolerance with onset or recognition during gestation places a patient in the category of gestational diabetes mellitus." --

Source: EMedicine, "Glucose Intolerance"

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glucose intolerance condition symptoms